Perry Meridian High School is a high school located at 400 W. Meridian School Road in Indianapolis, Indiana, 46217, on the far southside of the city. It is one of two public high schools serving grades nine through twelve in the Perry Township, along with Southport High School. At the beginning of the 2006-2007 school year, 2,224 students were enrolled at the school.

It is part of the Metropolitan School District of Perry Township.

The school colors are Navy Blue, Carolina Blue and Silver. The school mascot is the Falcon. The school mission statement is the acronym ACHIEVE for Accountability, Character, Honor, Integrity, Effort, Volunteer, Excellence.